A bit of a detour into neuroscience today with a look at the chemical structures of some of the major neurotransmitters in the brain. Inspired in part by this post on the chemicals related to various emotions.
All available to download as free A3 PDFs at the bottom of the accompanying post (http://wp.me/p4aPLT-6C).
A genetic disease has been cured in living, adult animals for the first time using a revolutionary genome-editing technique that can make the smallest changes to the vast database of the DNA molecule with pinpoint accuracy.
See on independent.co.uk
I’ve never been female. But I have been black my whole life. I can perhaps offer some insight from that perspective. There are many similar social issues related to access to equal opportunity that we find in the black community, as well as the community of women in a white male dominate society…
When I look at — throughout my life — I’ve known that I wanted to do astrophysics since I was 9 years old…I got to see how the world around me reacted to my expressions of these ambitions. All I can say is, the fact that I wanted to be a scientist, an astrophysicist was hands down the path of most resistance through the forces of society.
Anytime I expressed this interest, teachers would say, ‘Oh, don’t you wanna be an athlete?’ I want to become someone that was outside of the paradigm of expectations of the people in power. Fortunately, my depth of interest of the universe was so deep and so fuel enriched that everyone of these curve balls that I was thrown, and fences built in front of me, and hills that I had to climb, I just reach for more fuel, and I just kept going.
Now, here I am, one of the most visible scientists in the land, and I wanna look behind me and say, ‘Where are the others who might have been this,’ and they’re not there! …I happened to survive and others did not simply because of forces of society that prevented it at every turn. At every turn.
…My life experience tells me that when you don’t find blacks, when you don’t find women in the sciences, I know that these forces are real, and I had to survive them in order to get where I am today.
So before we start talking about genetic differences, you gotta come up with a system where there’s equal opportunity, then we can have that conversation."
"What’s up with chicks and science?"
Are there genetic differences between men and women, explain why more men are in science.
A research team led by the National Neuroscience Institute (NNI) has uncovered a novel function of the Amyloid Precursor Protein (APP), one of the main pathogenic culprits of Alzheimer’s disease. This discovery may help researchers understand how the protein goes awry in the brains of Alzheimer’s disease patients, and potentially paves the way for the development of innovative therapeutics to improve the brain function of dementia patients.
The findings were published in the prestigious scientific research journal Nature Communications last month. The study, which is led by Dr Zeng Li and her team from NNI, involved investigators from Duke-NUS Graduate Medical School and the Agency for Science and Technology (A*STAR).
Alzheimer’s disease is the most common form of dementia, which is set to rise significantly from the current 28,000 cases to 80,000 cases in 2030 among Singaporeans aged 60 and above. With a rapidly aging population, the burden of the disease will be profound affecting not just the person afflicted, but also the caregiver and family. While the exact cause of Alzheimer’s disease remains unknown, one of its pathological hallmarks is clear – the clumping of APP product in the brain when the protein is abnormally processed.
Finding out more about APP can help researchers gain a better understanding of the disease, and potentially identify biomarkers and therapeutic targets for it. However up till this point, little was known about the APP’s primary function in the brain.
Receptors for the messenger molecule serotonin can be modified in such a way that they can be activated by light. Together with colleagues, neuroscientists from the Ruhr-Universität Bochum (RUB) report on this finding in the journal “Neuron.” An imbalance in serotonin levels seems to cause anxiety and depression. The researchers have provided a new model system for investigating the mechanism underlying these dysfunctions in cell cultures as well as living organisms.
Olivia A. Masseck, Katharina Spoida, Deniz Dalkara, Takashi Maejima, Johanna M. Rubelowski, Lutz Wallhorn, Evan S. Deneris, Stefan Herlitze. Vertebrate Cone Opsins Enable Sustained and Highly Sensitive Rapid Control of Gi/o Signaling in Anxiety Circuitry. Neuron, 2014; 81 (6): 1263 DOI: 10.1016/j.neuron.2014.01.041
Way past it at this point. But yes.
Following on from his amazing series last week, here are Halley Docherty’s latest collages for us – well known historical paintings of city scenes around the world. See more